Disease Damage
Disease has been named as one of the types of damage in Diablo III. It is greenish/brown in appearance. Diseased targets suffer a damage debuff, dealing less damage and taking more from incoming attacks. The only official information about this damage type date to December 2010, and the property may have been changed or even removed since then.
No character skills currently list Disease as a damage type, but it may still be found as an item modifier, or as a damage type dealt by monsters.
Disease damage can be resisted with Poison resistance. It's not known if it can be reduced or absorbed, and it can not be blocked.
It's not known how critical hits interact with Disease damage.
Diablo III Damage Types
All that's known about Disease came from the @Diablo Twitter feed in December 2010.[1]
any change in the range of damage types to include holy, shadow, voodoo or anything else to match the classes? —Scyberdragon
Damage types will likely change some but are currently Physical, Fire, Lightning, Cold, Poison, Disease, Arcane, and Holy. —Diablo
Fairly significant in their difference, but both countered with a single resistance. Damage/resists aren’t design complete though.—Diablo
Whats the difference between poison and disease damage?—WickedBubba
Disease has a damage debuff (both intake and output), and poison has a health debuff (regen/heal). Subject to change of course.—Diablo
Is there much difference between poison and disease? They’re both internal maladies that hurt over a period of time.—Grug
