Cain is also the only character known to have survived when Tristram was destroyed by [[demon]]s, as they decide to put him in a gibbet instead of tearing him limb from limb like the other former citizens of Tristram (possibly under orders from the [[Prime Evils|three Brothers]] to keep him alive).

Heroes are alerted by the tragedy of Tristram by the [[Sisters of the Sightless Eye]], and rescues Cain before he is killed, or turned over to some greater demon. The rest of the year he spends following the heroes, assisting them with knowledge of the Prime Evils and Horadric artefacts, in order to permanently abolish the demonic forces on Sanctuary.

Image:Cain cinematic concept.jpg|Concept artwork for the [[cinematic]].

File:Cain-leah-chris-thunig.jpg|Concept preparation for the cinematic.

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