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A quest item required to complete The Doll quest. See the quest page for full details and a walkthrough.
The doll is just a child's doll, like a teddy bear, that's found in a special chest in the center of ruined Tristram. It must be taken to the well where the little girl's ghost is trapped. Once at the well, drop the doll and the girl will catch it and fly away, happy and free.