The Yshari Sanctum appears to be a specific structure belonging to the mage clans in Caldeum. The Yshari seem to be the council of sorcerers, and the Sanctum their main hall of reception and council. The structure is likely used only for councils of the higher sorcerers of the clans and visitors.
The Vizjerei sorcerer Valthek is part of the Yshari.
There are infamous chambers called the Bitter Depths located under the Sanctum.
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